NEPTIS® Perform Duo
Two Modes. One Module.
- [18F]FDG
- [18F]NaF
- [18F]FLT
- [18F]FMISO
- [18F]FHBG
- [18F]FCH
- [18F]FET
- [18F]FES
- [18F]PSMA1007
- [18F]F-L-DOPA
- [68Ga]Ga-tracers
- [177Lu]Lu-tracers
- Built on the proven NEPTIS® Perform (platform)
Produce the widest range of [18F] fluoride-based radiotracers where complex chemistry becomes routine and reliable production.
- R&D and routine onto one module
Develop tracer sequences without kits and produce them routinely on one module, with the same chemistries, cassettes and yields.
- Actuators
4 ramps of 5 three-position pneumatic actuators
- HPLC (option)
HPLC drawer and pathways, 1 injection valve, 1 rad detector (sensitivity < 2mCi) (WNE® technology)
- Detectors
5 rad detectors (+1 optional), 1 UV signal
- Hot cell compatibility
Fits standard shielded hot cells
- Syringe drivers
3 (30 mL and 10/3 mL)
- Dimensions
560 x 420 x 400 mm | 22.0 x 16.5 x 15.7 in (w x h x d)
- Heating & Reactor ovens
1 (+1 optional)
- Weight
38 kg / 84 lbs
- Sensors
Vacuum, flow and pressure
- Ready-to-use cassettes available
Yes
- UV detection
MWD UV detector via optical fibers (electronics protected)
- Software
Browser‑based NEPTIS® Control with Designer and Trending for method development and run analytics
- Two in One
Single-use cassettes for routine GMP production, reusable PEEK manifolds for development, with conversion in either direction. NEPTIS® Perform Duo is the only synthesizer that switches consumable mode on the same hardware and software.
- Reusable manifold
With reusable PEEK manifolds, each iteration costs only operator time and reagents. Over 30 reuses demonstrated in internal testing, using the NEPTIS® xSeed™ cleaning procedure.
- Reliable
Built with proven NEPTIS® Perform platform, with the same cassettes, chemistry, yields and workflow, so your team is productive on day one. Sequences developed move straight into routine production on the same module, with one qualification and one set of paperwork.
- Scalable
Start with a base configuration and grow with your pipeline. Add HPLC column selection, a quaternary pump, extra detectors or a second reactor oven, including FDG dual-run options as you need them.
Interested to learn more about NEPTIS® Perform Duo?
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- 19/10/2026
IBA launches NEPTIS® Perform Duo, one synthesizer module from tracer development to routine productionLouvain-la-Neuve, Belgium, October 19th, 7 a.m. - IBA (Ion Beam Applications S.A., EURONEXT), the world leader in particle accelerator technology and the leading provider of radiopharmaceutical production solutions, today announces it has unveiled NEPTIS® Perform Duo, a synthesizer that lets radiopharmaceutical producers develop new tracers and manufacture them on one module, on October 18 at the EANM'26 Congress in Vienna, Austria.
A radiopharmaceutical synthesizer is an automated system that combines a radioisotope with specific chemical compounds to produce a radiopharmaceutical for diagnostic imaging or therapeutic use. It plays a crucial role in radiopharmaceutical production by automating and precisely controlling the chemical processes required to transform a radioisotope into a safe, consistent and ready-to-use drug.
Developing a new PET imaging agent, known as a tracer, takes many trial runs. On most synthesizers, each run uses a new single-use kit. As a result, producers that both develop and manufacture tracers often rely on two separate systems.
NEPTIS® Perform Duo brings both steps onto one module. For development, it uses reusable components, reused more than 30 times in internal testing, which lowers consumable costs. For production, it runs the same single-use cassettes and chemistries as NEPTIS® Perform, including FDG, the most widely used PET tracer. Because the system stays the same, the process a team develops is the process it produces, with one qualification path.
It is the first new product from ORA, since IBA acquired ORA in December 2025. The launch reflects IBA's commitment to radiochemistry as it builds a fully integrated offering for radiopharmaceutical manufacturers. Designed for contract manufacturers, commercial radiopharmaceutical producers and radiopharmacy networks, the new module joins NEPTIS® Perform and NEPTIS® xSeed™ in the NEPTIS® range.
“Our customers increasingly develop the tracers they later manufacture, and they want to do both on the same platform,” said Loïk-Maël Nys, President of IBA RadioPharma Solutions.“NEPTIS® Perform Duo gives them a simpler and more economical way to take a new compound from first run to routine production. For the teams we work with, that helps bring new diagnostic options to patients sooner.”
ORA brings 20 years of radiochemistry expertise, with NEPTIS® synthesizers installed at more than 600 sites in over 50 countries. Combined with IBA's four decades of experience in cyclotrons, the machines that produce medical isotopes, this gives radiopharmaceutical producers one partner from isotope production to dose-ready radiopharmaceutical.
