The rising clinical value of quantitative cardiac perfusion PET

Dr Parthiban Arumugam highlighted the 2024 European Society of Cardiology and Multisocietal American Guidelines for the management of chronic coronary syndromes: Both guidelines advocate PET (Positron Emission Tomography)  with quantitative blood flow measurement in the above patient population.
 

The guidelines endorse perfusion PET as a preferred imaging option to SPECT for both obstructive and non-obstructive coronary syndromes. It is particularly valuable in the evaluation of microvascular disease and ANOCA/INOCA, as it precisely quantifies myocardial blood flow reserve (MBFR) by measuring absolute myocardial blood flow (MBF) during rest and peak stress— a unique routine clinical capability of perfusion PET.
 

Endorsement of quantitative perfusion PET by non imaging societal guidelines hopefully sees more utilization of this modality by cardiologists in the future.

Prof Dr Parthiban Arumugam

References:

European Heart Journal, Volume 45, Issue 36, 21 September 2024, Pages 3415–3537, https://doi.org/10.1093/eurheartj/ehae177 - click here

AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation. 2023 Aug 29;148(9):e9-e119. doi: 10.1161/CIR.0000000000001168 - click here