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IBA BUSINESS UPDATE – THIRD QUARTER 2021

Louvain-La-Neuve, Belgium, November 18, 2021 –IBA (Ion Beam Applications S.A., EURONEXT), the world leader in particle accelerator technology, today announces its business update for the third quarter ending 30 September 2021.   Group Overview Strong performance across all business lines Ongoing commitment to stakeholder approach, delivering the best offering to our customers and investing for long-term sustainable growth whilst meeting ESG targets Strong balance sheet maintained, with EUR 91 million unaudited net cash (30 June 2021: EUR 69 million) Olivier Legrain, Chief Executive Officer of IBA commented:“IBA has continued to perform strongly in the second half of 2021 with solid progress across all business units. We have a highly active pipeline of new opportunities and are particularly excited about the marked revival in proton therapy activity in the important US market. Our Other Accelerators and Dosimetry businesses have also been exceptionally strong in the second half of the year with encouraging momentum as we approach 2022. “A core component of our roadmap towards sustainable growth is investment in future innovation to deliver strategic impact. In this regard, we were pleased to provide updates on a range of initiatives at the recent ASTRO conference, as well as several strategic partnerships, including in the promising field of radiotherapeutics. We are very excited about future prospects across our business lines and are in a confident position to achieve long-term profitability, with our stakeholder approach underpinning all of our business activities.”   Business Unit Highlights (including post-period end)   Proton Therapy 13 Proteus®ONE[1] and 8 Proteus®PLUS1 projects currently ongoing. Strong pipeline of new global opportunities with significant activity in the US and Asia Contract signed for a five room Proteus®PLUS System in China including a multi-year service contract Post-period end, finalized contract with Advocate Radiation Oncology in Florida, which previously selected IBA’s Proteus®ONE for its new Radiation Oncology Centre, including a multi-year service contract Post-period end, announced updates at ASTRO, including expansion of strategic partnership with RaySearch within Flash and proton ARC therapy projects, and the launch of Campus, the world’s first online proton therapy platform   Other Accelerators (RadioPharma, Industrial) and Dosimetry Strong performance in Other Accelerators in the third quarter, with 23 machines sold in the year to date of which 11 machines were sold in Asia Strategic R&D partnership announced with SCK CEN to enable the production of Actinimum-225 (Ac-225), a novel therapeutic radioisotope which has significant potential in the treatment of cancer Post-period end, announced a strategic partnership with TRAD Tests & Radiations to enable the development of a new radiation processing module, addressing an increasing unmet need in the sterilization market Dosimetry revenues and order book have continued to strengthen, further demonstrating the success of the business unit’s recent product launches   Outlook During the third quarter of 2021, IBA’s performance has continued to accelerate with strong progress across all business lines. Our pipeline is very active, particularly in the US and in Asia, and, coupled with the robust balance sheet and predictable revenue base of the services business, provides encouraging visibility for the period ahead. Whilst we are confident about business performance, the ongoing complex situation with the pandemic means that we are still unable to provide reliable financial guidance. We will provide a further update at the time of the 2021 full year results in March 2022.   [1]*Proteus®ONE and Proteus®PLUS are brand names of Proteus 235
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rigging cyclotron korea

Rigging of the Cyclone® 70 at the Institute of Basic Science in Korea

When a 140 tons cyclotron has to be placed into its vault, it is always impressive ! It requires precision expertise and a close attention to every details. The IBA Cyclone® 70 MeV Cyclotron was successfully rigged by part before being reassembled in the vault of the Institute of Basic Science in Korea. It is now time to celebrate and congratulate all the people involved in this important project's milestone.   About the project The Institute of Basic Science (IBS) is constructing equipment and facilities for the Rare isotope Accelerator complex for ON-line experiments (RAON). RAON is a large basic science research facility built around a heavy-ion accelerator. When completed, it will be a key pillar of the International Science and Business Belt (ISBB). This will be an optimal facility to produce and study new rare isotopes, so the global scientific community is closely following its progress. The Cyclone®70 will be one of the drivers of the RAON facility. Scientists have discovered approximately 3,000 isotopes to date, but they believe an additional 7,000 isotopes have yet to be discovered, presenting unlimited potential for rare isotope science. When the operation of RAON begins, new research opportunities will open up in various areas, such as research into the origin of elements, discovery of new rare isotopes and the study of their structure, and applied research in material and biomedical sciences.
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Videos

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The Impressive Rigging of the Cyclone KIUBE Through a Shielded Door

Thanks to its compact design, the Cyclone® KIUBE entered through the door of the existing vault! This technical exploit can be achieved only by IBA.

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Maximize your production capacity with the Synthera+

FP™ AUTOMATED LOADER *MULTIPLY YOUR PRODUCTION CAPABILITY BY 4

The IFP™ Loader* enables you to carry out independent multiple runs of multiple molecules or of a single tracer.Four consecutive runs can be performed without opening the hot cell with ZERO radiation exposure to the operator and ZERO downtime between runs.You can add up to 3 Synthera®+ with the IFP Loader within the same selected hot cell: up to 12 runs of multiple tracers without opening the hot cell!More capacity with the benefit of not having to invest in more hot cells.

* Patent application EP3308852A1

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INTEGRALAB®PLUS is a fully integrated solution, combining equipment and services for establishing a radiopharmaceutical GMP production centre tailored to your precise needs. Our approach is truly comprehensive, taking your project from building design through to ongoing production with full regulatory compliance and the selection, integration, installation and qualification of equipment that meets your radioisotope production goals