123I can be produced on a cyclotron using proton bombardment (28- 30MeV) of a 124Xenon gas target.
123 gas target
Gas target loaded with enriched 124Xenon to provide 123I by natural decay. The gas target has a cryogenic recovery system for 124Xe (working in closed loop). The 123I is extracted by washing target with pure water.
The target wash solution is purified by two ion exchange columns to provide a concentrated NaI solution for dispensing or labelling