IBA Business Update – Third Quarter 2022
Rigging of the Cyclone® KIUBE at Neijang
Educational Webinar Library
Is PET the future of nuclear cardiology- why?
From new radiochemistry developments to clinical routine applications
How to set up a GMP radiopharmacy?
The clinical value PET myocardial blood flow quantification and practical aspects of implementing a Cardiac PET Program
Set-up of a commercial Ac-225 production facility
Willem Leysen, Jakub Damian, Lucia-Ana Popescu, Jasper Mermans, Hanna Skliarova, Dominic Maertens, Stephan Heinitz, Guy Scheveneels, Koen Hasaers, Dennis Elema, Sven Van Den Berghe, Cristiana Gameiro, Jean-Michel Geets, Samy Bertrand
Automated cassette-based synthesis of [18F]FAPI-74 via [18F]AlF strategy for routine production in a GMP environment
N. Emmanuel, D. Goblet, G. Decoux, V. Kramer, F. Valla, J. Agudelo
Detailed study of the distribution of activation inside the magnet coils of a compact PET cyclotron
V. Bonvin , F. Bochud , J. Damet , C. Theis , H. Vincke , R. Geyer
Securing Gallium-68 availability with liquid target production on mid-energy cyclotrons: Users' experience
C. Gameiro , V. H. Alves , A. Abrunhosa , F. Alves , D. Goblet , B. Nactergal , A. Uhlending , V. Hugenberg , T. Ortgies , G. Hoeger , J. Manrique-Arias , R. Freifelder , K. Hye-Yeong , M. Bhuiyan, A. Kucharski
IBA Synthera +
Synthera®+ remains the most compact module on the market: up to 3 synthesizers can fit into a standard hot cell. Synthera®+ and Synthera®+ HPLC have both been fully redesigned to meet the most demanding production schedule of different radiotracers without opening the hot cell (less intervention, more safety). Synthera®+ can be equipped with the automatic IFP Loader (disposable production cassette dispenser) which can stack up to 4 cassettes. This allows it to perform consecutive runs of different compounds without opening the hot cell, resulting in nearly zero radiation exposure to the operator. This unique feature multiplies the capability of each module by a factor of four.
Synthera® Extension complements the functionality of the Synthera® family platform with its additional valves and a syringe driver for more complex processes such as postprocess purification in 68Ga liquid target productions* and elution of Ge/Ga generator when necessary.** [18F]NaF can also be produced on Synthera® Extension on routine basis. Additionally, diverse research applications have been developed on the Synthera® Extension as a standalone module, such as : (18F)NaF; separation/purification of 89Zr, 64Cu, 99mTc to obtain 89Zr-oxalate, 64Cu-chloride, 99mTc-pertechnetate, respectively. The module employs a re-usable support cassette where disposable tubing can be placed, which eliminates the need to use an additional IFP™ for complex syntheses.
*Patent pending on the complete liquid target process: EP15170854
***It depends on the type of generator.