O15Oxygen 15

Oxygen-15 is an isotope used in positron emission tomography (PET). It has a half-life of about 2 minutes. There are several uses for this isotope: 15O for oxygen consumption measurements, [15O]CO for lung perfusion and mainly as 15O-water used for measuring regional cerebral blood and for myocardial perfusion imaging.

To produce Oxygen 15,
we recommend this production route:

  • Recommended

    Cyclone:

    Cyclone® 3D

    The Cyclone® 3D was developed to answer a need of Oxygen-15 production. It is capable of accelerating deuterons up to around 3.4MeV and produces 15O using the 14N(d,n)15O nuclear reaction.

    Target:

    Nirta® Gas target

    Nirta® Gas target is an irradiation system for the production of [15O]O2 or [15O]CO. The irradiation of Nitrogen-14  with deuteron produces the 14N(d,n)15O nuclear reaction.

    More about Nirta® gas target

    Chemistry:

    Pinctada® water

    IBA Pinctada® water is a fully automated module that employs effective flow chemistry to produce high yield of [15O]H2O in batch mode

    More about Pinctada® water

  • Alternative

    Cyclone:

    Cyclone® KIUBE

    Download the brochure

    To produce 15O a cyclotron using positively charged ions, the optimal energy to reach the target is 13 MeV. The Cyclone®  KIUBE is equipped with a degrador foil on the 15O target  to reach the 13 MeV.

    More about Cyclone® KIUBE

    Target:

    Nirta® Gas target

    Nirta® Gas target is an irradiation system for the production of [15O]O2 or [15O]CO. The irradiation of low volume of enriched 15N with proton produces the 15O isotope.

    More about Nirta® gas target

    Chemistry:

    Pinctada® water

    IBA Pinctada® water is a fully automated module that employs effective flow chemistry to produce high yield of [15O]H2O in batch mode

    More about Pinctada® water

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