The IBA Cyclone® KIUBE 300 has the highest production capacity ever reached by a PET cyclotron with its ability to produce up to 300 FDG* doses in a 2-hour run.

Louvain-la-Neuve, Belgium, June 18th 2018 - IBA (Ion Beam Applications S.A., EURONEXT), the world’s leading provider of solutions for the diagnosis and treatment of cancer, today announces high level production results achieved by its fixed-energy cyclotron, the Cyclone® KIUBE 300μA, installed at the University Hospital UZ Brussel in Belgium.

IBA’s Cyclone® KIUBE was quickly established as the mid-energy cyclotron of choice after its launch due to its high production capacity and compact size. Cyclone® KIUBE is a true evolutionary cyclotron, meaning that production capacity can be increased step-by-step: from 10, 16, 20 to reach 30 Curies (1110 GBq) of F-18 in a two-hour run, enabling the PET centers to meet the increasing demand for fluorodeoxyglucose (“FDG”), a key element in clinical PET imaging.

Bruno Scutnaire, Head of RadioPharma Solutions at IBA, commented: “Nowadays, radiopharmacies need to produce an increasing amount of FDG in a limited time and to produce numerous other compounds the same day. Short-lived isotopes used in PET cannot be stockpiled and must be produced daily. The Cyclone® KIUBE 300 is the perfect solution with its ability to produce large batches of FDG while offering a large panel of targets and chemistry solutions for non-conventional radioisotope production.”
“We selected IBA’s Cyclone® KIUBE 300 because it is the highest production capacity cyclotron in the market and it has two independent ion sources,” said Dr Tony Lahoutte, Head of the Nuclear Medicine Department at UZ Brussel. “It allows us to answer the increasing demand of FDG while saving time for other isotope production with its eight exit ports.”
“We are impressed by the reliability of our Cyclone® KIUBE. The interface is user-friendly and simple to use and we can rely on the automatic production mode to deliver the required quantities of F-18.”said Vicky Caveliers, Head of Radiopharmacy at UZ Brussel.
*fluorodeoxyglucose labelled with F-18 is the most commonly used radiotracer in positron emission molecular imaging.