How to produce <strong>Astatine 211</strong>

Cyclotron
Target
Chemistry
Optimized production route
Cyclone® 30 XP

Cyclone® 30 XP

<p><sup>211</sup>At is produced with a cyclotron using alpha beam at 30 MeV</p> More about Cyclone® 30
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Nirta® Solid target 30 MeV

Nirta® Solid target 30 MeV

<p><sup>209</sup>Bi (nat-Bismuth)&nbsp;is irradiated &nbsp;in the solid target creating <sup>209</sup>Bi(α,3n)<sup>211</sup>At nuclear reaction.&nbsp;</p>
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Thermodistilation module

Thermodistilation module

<p><span lang="EN-US"><span>Irradiated target is place in the module and </span></span><sup>211</sup>At<span lang="EN-US"><span> is extracted&nbsp; via thermodistillation</span></span></p>
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Resources

Scientific publications

Automated synthesis of N-succinimidyl 3-[[sup]211[/sup]At]astatobenzoate (SAB) for antibodies radiolabelling.

Holisoa Rajerison, François Guérard, Mickael Bourgeois, Isidro Da Silva, Christophe Sauvage, Ferid Haddad, Jacques Barbet, Alain Faivre-Chauvet, Jean-François Gestin

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